New Avenues in Male Reproductive Health


New Avenues in Male Reproductive Health

Male infertility and male hypogonadism are common reproductive disorders that present in different forms, affecting many aspects of health. However, recent studies have uncovered new ways to improve men's reproductive health. For example, mapping of genetic pathways and novel molecular approaches have allowed us to interrogate mechanisms underlying testicular function which lead to pathology. These may also lead to the development of novel drug therapies to modulate testicular function.

This timely special collection will pull together an array of research focused on improving the treatment of male reproductive disorders. It will cover topics including:

  • Genetic disorders in male infertility, including genetics of hypogonadotropic hypogonadism
  • Sperm maturation during transport through the male reproductive tract
  • Environmental threats for male reproductive health
  • Dysregulation of testicular function by obesity or diabetes
  • Novel seminal or sperm diagnostic markers of male reproductive function
  • Putative therapeutic targets or therapies for male infertility
  • Efficacy of treatment with FSH for infertile male patients
  • Sperm methylome/transcriptome/proteome and embryo development/offspring health
  • Microbiome and reproductive health
  • In vitro spermatogenesis.

“This collection has the potential to bring together studies from the latest and most interesting lines of research, promising a better understanding of the causes of male infertility and the identification of new therapeutic approaches.” – Collection editor, Professor Aldo Calogero. 

Contribute to this important field of research by submitting an original research article or review via our submission portal, or for more information and to submit your proposal, please email

This collection has partnered with 'Reproductive Endocrinology 2024' , a new event from the Society for Endocrinology. 

Society for Endocrinology Reproductive Endocrinology event. 3 December 2024, London, UK.


Collection Editors:

Dr Channa Jayasena

Dr. Channa Jayasena – Guest Editor

Dr Jayasena is a Reader in Reproductive Endocrinology at Imperial College London, where he currently leads a research team. Dr Jayasena works as a Consultant in Reproductive Endocrinology and Head of Andrology at St. Mary's Hospital and Hammersmith Hospital, London.

Dr Anu Sironen

Dr. Anu Sironen – Guest Editor

Dr. Sironen, University College London (UCL), is currently working on a UK Biotechnology and Biological Sciences Research Council (BBSRC) funded research project to understand the cilia related causes and mechanisms in male infertility. She is a Senior Research Scientist at UCL and Natural Resources Institute Finland, where her studies have identified several genetic causes of male infertility in animal models and in human patients.

Professor Aldo E. Calogero

Professor Aldo E. Calogero, M.D. – Guest Editor

Professor Calogero is a Full Professor of Endocrinology at the University of Catania, Catania, Italy. He is Director of the Division of Endocrinology, Metabolic Diseases and Nutrition of the German University Hospital Policlinico “G. Rodolico – San Marco”, Catania, Italy.